A new auto-inflammatory disease – LAVLI

Scientists have identified an auto-inflammatory disease caused by mutations in the LYN gene, an important regulator of immune responses in health and disease. Named Lyn kinase-associated vasculopathy and liver fibrosis (LAVLI), the identification sheds light on how genes linked to certain illnesses can potentially be targets for treatment by repurposing existing drugs. The research is…

Spring Allergy: The Struggle Is Real

They say “one man’s meat is another man’s poison”, and we can’t agree more. This is totally true especially when you ask people: “What does Spring mean to you?”.  Some might say that it is the emblem of a fresh start and the end of their winter blues. Others might state that spring is the…

Genetic causes of unexplained rare diseases are identified

Using a new computational approach developed to analyze large genetic datasets from rare disease cohorts, researchers at the Icahn School of Medicine at Mount Sinai and colleagues including the University of Bristol, have discovered previously unknown genetic causes of three rare conditions: primary lymphedema (characterized by tissue swelling), thoracic aortic aneurysm disease, and congenital deafness.…

Vitamin D is effective in treating skin rashes

Vitamin D has been shown to be effective in treating skin rashes resulting from chemical exposure, scientists from Northwestern Medicine have found. In a double randomized trial. The results are published in the journal JCI Insight. The scientists analyzed tissue samples from 28 healthy participants: the skin of their hands on the inside of their…

Encouraging results of first-in-human trial of temperature-stable tuberculosis vaccine candidate

The Access to Advanced Health Institute (AAHI) published results of a Phase 1 clinical trial demonstrating the safety and immune responses in a new vaccine against tuberculosis (TB), the world’s second deadliest infectious disease (NCT03722472). AAHI’s TB vaccine combines several proteins from Mycobacterium tuberculosis (Mtb), the bacterium that causes TB, into a fusion protein (“ID93”)…

Extending life by Eight years

Adults who live a heart-healthy lifestyle, as measured by the American Heart Association’s Life’s Essential 8 (LE8) cardiovascular health scoring, tend to live longer lives free of chronic disease. The preliminary studies will be presented at the American Heart Association’s Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Scientific Sessions 2023, held in Boston, February 28-March 3,…